Researchers Study Life After Death — And It Gets Weirder

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exclusively outside of what typically defines life and death.

The fact that practices such as organ donation allow organs, tissues, and cells to continue function – even after a living organism has passed away – raises the question: What mechanisms allow certain cells to remain operational after death has occurred?

(However, I can provide a paraphrased version of the title “with new functions after death”)


It’s intriguing to reflect on the cycle of existence that unfolds through the realms of life, death, and the emergence of something entirely new.

Permanently malfunctioning state machine states that do not improve or create new functions are not considered part of the third state.

These organisms show behaviors that go way beyond their natural biological purposes. Specifically, these xenobots use their cilia, tiny hair-like structures, to move around and navigate their environment. In a living frog embryo, cilia are usually used to move mucus.

They can exactly replicate their body structure and features without developing, as opposed to usual reproduction methods that involve growth within or on the organism itself.

Scientists have found that certain robots have learned to adapt and act in novel ways. They are not only able to navigate their surroundings but also fix both themselves and damaged robotic cells nearby.

These findings indicate that cellular systems are highly adaptable and therefore, cells and organisms are not limited to evolving in only predetermined ways. Moreover, the third state implies that when organisms die, it can influence how life changes over time.


Postmortem conditions

These include examination of whether certain cells and tissues can endure and work following an organism’s death. This involves studying environmental conditions, the level of metabolic activity, and preservation methods.

Some tissues, including the liver, heart, and spleen, can remain cultured even a month after death.

Existing technologies can enable tissue samples such as bone marrow to mimic the functionality of samples from living donors.

Have a seriously negative impact on tissue and cell survival rates.

People who have islet cells, which make insulin in the pancreas, receive transplants from donors. Researchers think that autoimmune responses, the high energy costs, and the breakdown of protective mechanisms could be the main reasons why many islet transplant attempts are unsuccessful.

These channels and pumps produce electrical signals that enable cells to communicate with each other and carry out specific processes like growth and movement, ultimately defining the shape and structure of the organism they make up.

Indicating a broad capacity for transformation across various types of cells.


Implications for biology and medicine

The third condition not only provides new perspectives on the adaptability of cells. It also offers possibilities for new treatments.

From a person’s living tissue, it may be possible to deliver medicine without causing the immune system to overreact. Engineered anthrobots injected into the body could potentially dissolve blockages in the arteries in patients with atherosclerosis and remove excess mucus in cystic fibrosis patients.

This “kill switch” prevents the growth of potentially invasive cells.

Further understanding how certain cells remain active and transform into multiple cellular units even after the death of an organism could potentially lead to advancements in personalized and preventive medical treatments.



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